Search on: POLYMERASE, MITOCHONDRIAL DNA 
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Descriptor English:   DNA Polymerase gamma 
Descriptor Spanish:   Polimerasa del ADN Mitocondrial 
Descriptor Portuguese:   Polimerase do DNA Mitocondrial 
Synonyms English:   DNA Polymerase, Mitochondrial
Mitochondrial DNA Polymerase
Polymerase gamma, DNA
Polymerase, Mitochondrial DNA  
Tree Number:   D08.811.913.696.445.308.300.169
D12.776.575.280
Definition English:   A DNA-directed DNA polymerase that functions in the replication of MITOCHONDRIAL DNA. Mutations in the gene that encodes this enzyme (POLG) are associated with some forms of OPHTHALMOPLEGIA, CHRONIC EXTERNAL PROGRESSIVE. 
History Note English:   2018 (1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   57031 
Unique Identifier:   D000074002 

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